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A case report on the efficacy of vigabatrin analogue (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) in a patient with infantile spasms

West Syndrome is characterized by infantile spasms, a hypsarrhythmic electroencephalogram (EEG) pattern, and a poor neurodevelopmental prognosis. First-line treatments include adrenocorticotrophic hormone (ACTH) and vigabatrin, but adverse effects often limit their use. CPP-115 is a high-affinity vi...

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Detalles Bibliográficos
Autores principales: Doumlele, Kyra, Conway, Erin, Hedlund, Julie, Tolete, Patricia, Devinsky, Orrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024311/
https://www.ncbi.nlm.nih.gov/pubmed/27668180
http://dx.doi.org/10.1016/j.ebcr.2016.08.002