Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis

BACKGROUND: The mechanisms involved in lung cancer (LC) progression are poorly understood making discovery of successful therapies difficult. Adaptor proteins play a crucial role in cancer as they link cell surface receptors to specific intracellular pathways. Intersectin-1s (ITSN-1s) is an importan...

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Detalles Bibliográficos
Autores principales: Jeganathan, Niranjan, Predescu, Dan, Zhang, Jin, Sha, Fei, Bardita, Cristina, Patel, Monal, Wood, Stephen, Borgia, Jeffrey A., Balk, Robert A., Predescu, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024437/
https://www.ncbi.nlm.nih.gov/pubmed/27629044
http://dx.doi.org/10.1186/s12943-016-0543-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024437/
https://www.ncbi.nlm.nih.gov/pubmed/27629044
http://dx.doi.org/10.1186/s12943-016-0543-1

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