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Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis

BACKGROUND: The mechanisms involved in lung cancer (LC) progression are poorly understood making discovery of successful therapies difficult. Adaptor proteins play a crucial role in cancer as they link cell surface receptors to specific intracellular pathways. Intersectin-1s (ITSN-1s) is an importan...

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Detalles Bibliográficos
Autores principales:	Jeganathan, Niranjan, Predescu, Dan, Zhang, Jin, Sha, Fei, Bardita, Cristina, Patel, Monal, Wood, Stephen, Borgia, Jeffrey A., Balk, Robert A., Predescu, Sanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024437/ https://www.ncbi.nlm.nih.gov/pubmed/27629044 http://dx.doi.org/10.1186/s12943-016-0543-1

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