HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway

BACKGROUND: HSV-2 is the major cause of genital herpes. We previously demonstrated that the host viral restriction factor tetherin restricts HSV-2 release and is antagonized by several HSV-2 glycoproteins. However, the mechanisms underlying HSV-2 glycoproteins mediated counteraction of tetherin rema...

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Detalles Bibliográficos
Autores principales: Liu, Yalan, Li, Mei, Zhang, Di, Zhang, Mudan, Hu, Qinxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024446/
https://www.ncbi.nlm.nih.gov/pubmed/27630089
http://dx.doi.org/10.1186/s12985-016-0610-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024446/
https://www.ncbi.nlm.nih.gov/pubmed/27630089
http://dx.doi.org/10.1186/s12985-016-0610-7

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