Development of a high throughput drug screening assay to identify compounds that protect oligodendrocyte viability and differentiation under inflammatory conditions

BACKGROUND: Newly proliferated oligodendrocyte precursor cells (OPCs) migrate and surround lesions of patients with multiple sclerosis (MS) and other demyelinating diseases, but fail to differentiate into oligodendrocytes (OLs) and remyelinate remaining viable axons. The abundance of secreted inflam...

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Detalles Bibliográficos
Autores principales: Lariosa-Willingham, Karen D., Rosler, Elen S., Tung, Jay S., Dugas, Jason C., Collins, Tassie L., Leonoudakis, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024459/
https://www.ncbi.nlm.nih.gov/pubmed/27629829
http://dx.doi.org/10.1186/s13104-016-2219-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024459/
https://www.ncbi.nlm.nih.gov/pubmed/27629829
http://dx.doi.org/10.1186/s13104-016-2219-8

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