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Electrochemotherapy with bleomycin is effective in BRAF mutated melanoma cells and interacts with BRAF inhibitors

BACKGROUND: The aim of the study was to explore the effectiveness of electrochemotherapy (ECT) during the treatment of melanoma patients with BRAF inhibitors. Its effectiveness was tested on BRAF mutated and non-mutated melanoma cells in vitro and in combination with BRAF inhibitors. MATERIALS AND M...

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Detalles Bibliográficos
Autores principales: Dolinsek, Tanja, Prosen, Lara, Cemazar, Maja, Potocnik, Tjasa, Sersa, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024665/
https://www.ncbi.nlm.nih.gov/pubmed/27679543
http://dx.doi.org/10.1515/raon-2016-0042