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Controlling secretion to limit chemoresistance

The tumor microenvironment influences cancer progression and therapy outcome by mechanisms not yet fully understood. In this issue of Genes & Development, Bent and colleagues (pp. 1811–1821) show how chemotherapy causes endothelial senescence. Interestingly, senescent endothelial cells do not mo...

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Detalles Bibliográficos
Autores principales: Georgilis, Athena, Gil, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024677/
https://www.ncbi.nlm.nih.gov/pubmed/27601527
http://dx.doi.org/10.1101/gad.288571.116