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Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation

Brown adipocytes display phenotypic plasticity, as they can switch between the active states of fatty acid oxidation and energy dissipation versus a more dormant state. Cold exposure or β-adrenergic stimulation favors the active thermogenic state, whereas sympathetic denervation or glucocorticoid ad...

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Detalles Bibliográficos
Autores principales: Zeng, Xing, Jedrychowski, Mark P., Chen, Yi, Serag, Sara, Lavery, Gareth G., Gygi, Steve P., Spiegelman, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024681/
https://www.ncbi.nlm.nih.gov/pubmed/27566776
http://dx.doi.org/10.1101/gad.285312.116