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Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation
Brown adipocytes display phenotypic plasticity, as they can switch between the active states of fatty acid oxidation and energy dissipation versus a more dormant state. Cold exposure or β-adrenergic stimulation favors the active thermogenic state, whereas sympathetic denervation or glucocorticoid ad...
Autores principales: | Zeng, Xing, Jedrychowski, Mark P., Chen, Yi, Serag, Sara, Lavery, Gareth G., Gygi, Steve P., Spiegelman, Bruce M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024681/ https://www.ncbi.nlm.nih.gov/pubmed/27566776 http://dx.doi.org/10.1101/gad.285312.116 |
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