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Direct interrogation of the role of H3K9 in metazoan heterochromatin function

A defining feature of heterochromatin is methylation of Lys9 of histone H3 (H3K9me), a binding site for heterochromatin protein 1 (HP1). Although H3K9 methyltransferases and HP1 are necessary for proper heterochromatin structure, the specific contribution of H3K9 to heterochromatin function and anim...

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Detalles Bibliográficos
Autores principales: Penke, Taylor J.R., McKay, Daniel J., Strahl, Brian D., Matera, A. Gregory, Duronio, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024684/
https://www.ncbi.nlm.nih.gov/pubmed/27566777
http://dx.doi.org/10.1101/gad.286278.116