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Unbiased identification of signal-activated transcription factors by barcoded synthetic tandem repeat promoter screening (BC-STAR-PROM)

The discovery of transcription factors (TFs) controlling pathways in health and disease is of paramount interest. We designed a widely applicable method, dubbed barcorded synthetic tandem repeat promoter screening (BC-STAR-PROM), to identify signal-activated TFs without any a priori knowledge about...

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Detalles Bibliográficos
Autores principales: Gosselin, Pauline, Rando, Gianpaolo, Fleury-Olela, Fabienne, Schibler, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024686/
https://www.ncbi.nlm.nih.gov/pubmed/27601530
http://dx.doi.org/10.1101/gad.284828.116