Heme acquisition in the parasitic filarial nematode Brugia malayi

Nematodes lack a heme biosynthetic pathway and must acquire heme from exogenous sources. Given the indispensable role of heme, this auxotrophy may be exploited to develop drugs that interfere with heme uptake in parasites. Although multiple heme-responsive genes (HRGs) have been characterized within...

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Detalles Bibliográficos
Autores principales: Luck, Ashley N., Yuan, Xiaojing, Voronin, Denis, Slatko, Barton E., Hamza, Iqbal, Foster, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024691/
https://www.ncbi.nlm.nih.gov/pubmed/27363426
http://dx.doi.org/10.1096/fj.201600603R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024691/
https://www.ncbi.nlm.nih.gov/pubmed/27363426
http://dx.doi.org/10.1096/fj.201600603R

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