Cargando…

Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability

[Image: see text] There is a compelling and growing need to accurately predict the impact of amino acid mutations on protein stability for problems in personalized medicine and other applications. Here the ability of 10 computational tools to accurately predict mutation-induced perturbation of foldi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kroncke, Brett M., Duran, Amanda M., Mendenhall, Jeffrey L., Meiler, Jens, Blume, Jeffrey D., Sanders, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024705/
https://www.ncbi.nlm.nih.gov/pubmed/27564391
http://dx.doi.org/10.1021/acs.biochem.6b00537