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Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents

Neuropathy is a serious complication of diabetes that has a significant socioeconomic impact, since it frequently demands high levels of health care consumption and compromises labor productivity. Recently, LASSBio-1471 (3) was demonstrated to improve oral glucose tolerance, reduce blood glucose lev...

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Detalles Bibliográficos
Autores principales: Zapata-Sudo, Gisele, da Costa Nunes, Isabelle Karine, Araujo, Josenildo Segundo Chaves, da Silva, Jaqueline Soares, Trachez, Margarete Manhães, da Silva, Tiago Fernandes, da Costa, Filipe P, Sudo, Roberto Takashi, Barreiro, Eliezer J, Lima, Lídia Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024769/
https://www.ncbi.nlm.nih.gov/pubmed/27672310
http://dx.doi.org/10.2147/DDDT.S108327