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Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents
Neuropathy is a serious complication of diabetes that has a significant socioeconomic impact, since it frequently demands high levels of health care consumption and compromises labor productivity. Recently, LASSBio-1471 (3) was demonstrated to improve oral glucose tolerance, reduce blood glucose lev...
Autores principales: | Zapata-Sudo, Gisele, da Costa Nunes, Isabelle Karine, Araujo, Josenildo Segundo Chaves, da Silva, Jaqueline Soares, Trachez, Margarete Manhães, da Silva, Tiago Fernandes, da Costa, Filipe P, Sudo, Roberto Takashi, Barreiro, Eliezer J, Lima, Lídia Moreira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024769/ https://www.ncbi.nlm.nih.gov/pubmed/27672310 http://dx.doi.org/10.2147/DDDT.S108327 |
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