Exposure-response analysis to assess the concentration–QTc relationship of CC-122

CC-122 hydrochloride is a novel pleiotropic pathway modifier compound that binds cereblon, a substrate receptor of the Cullin 4 RING E3 ubiquitin ligase complex. CC-122 has multiple activities including modulation of immune cells, antiproliferative activity of multiple myeloma and lymphoma cells, an...

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Detalles Bibliográficos
Autores principales: Li, Yan, Carayannopoulos, Leonidas N, Thomas, Michael, Palmisano, Maria, Zhou, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024774/
https://www.ncbi.nlm.nih.gov/pubmed/27672344
http://dx.doi.org/10.2147/CPAA.S111867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024774/
https://www.ncbi.nlm.nih.gov/pubmed/27672344
http://dx.doi.org/10.2147/CPAA.S111867

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