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Exposure-response analysis to assess the concentration–QTc relationship of CC-122

CC-122 hydrochloride is a novel pleiotropic pathway modifier compound that binds cereblon, a substrate receptor of the Cullin 4 RING E3 ubiquitin ligase complex. CC-122 has multiple activities including modulation of immune cells, antiproliferative activity of multiple myeloma and lymphoma cells, an...

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Detalles Bibliográficos
Autores principales:	Li, Yan, Carayannopoulos, Leonidas N, Thomas, Michael, Palmisano, Maria, Zhou, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024774/ https://www.ncbi.nlm.nih.gov/pubmed/27672344 http://dx.doi.org/10.2147/CPAA.S111867

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