Aspects of T Cell-Mediated Immunity Induced in Mice by a DNA Vaccine Based on the Dengue-NS1 Antigen after Challenge by the Intracerebral Route

Dengue disease has emerged as a major public health issue across tropical and subtropical countries. Infections caused by dengue virus (DENV) can evolve to life-threatening forms, resulting in about 20,000 deaths every year worldwide. Several animal models have been described concerning pre-clinical...

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Detalles Bibliográficos
Autores principales: Oliveira, Edson R. A., Gonçalves, Antônio J. S., Costa, Simone M., Azevedo, Adriana S., Mantuano-Barradas, Marcio, Nogueira, Ana Cristina M. A., Alves, Ada M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024998/
https://www.ncbi.nlm.nih.gov/pubmed/27631083
http://dx.doi.org/10.1371/journal.pone.0163240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024998/
https://www.ncbi.nlm.nih.gov/pubmed/27631083
http://dx.doi.org/10.1371/journal.pone.0163240

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