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Aspects of T Cell-Mediated Immunity Induced in Mice by a DNA Vaccine Based on the Dengue-NS1 Antigen after Challenge by the Intracerebral Route
Dengue disease has emerged as a major public health issue across tropical and subtropical countries. Infections caused by dengue virus (DENV) can evolve to life-threatening forms, resulting in about 20,000 deaths every year worldwide. Several animal models have been described concerning pre-clinical...
Autores principales: | Oliveira, Edson R. A., Gonçalves, Antônio J. S., Costa, Simone M., Azevedo, Adriana S., Mantuano-Barradas, Marcio, Nogueira, Ana Cristina M. A., Alves, Ada M. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024998/ https://www.ncbi.nlm.nih.gov/pubmed/27631083 http://dx.doi.org/10.1371/journal.pone.0163240 |
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