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A Recombination Directionality Factor Controls the Cell Type-Specific Activation of σ(K) and the Fidelity of Spore Development in Clostridium difficile
The strict anaerobe Clostridium difficile is the most common cause of nosocomial diarrhea, and the oxygen-resistant spores that it forms have a central role in the infectious cycle. The late stages of sporulation require the mother cell regulatory protein σ(K). In Bacillus subtilis, the onset of σ(K...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025042/ https://www.ncbi.nlm.nih.gov/pubmed/27631621 http://dx.doi.org/10.1371/journal.pgen.1006312 |