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A Recombination Directionality Factor Controls the Cell Type-Specific Activation of σ(K) and the Fidelity of Spore Development in Clostridium difficile

The strict anaerobe Clostridium difficile is the most common cause of nosocomial diarrhea, and the oxygen-resistant spores that it forms have a central role in the infectious cycle. The late stages of sporulation require the mother cell regulatory protein σ(K). In Bacillus subtilis, the onset of σ(K...

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Detalles Bibliográficos
Autores principales: Serrano, Mónica, Kint, Nicolas, Pereira, Fátima C., Saujet, Laure, Boudry, Pierre, Dupuy, Bruno, Henriques, Adriano O., Martin-Verstraete, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025042/
https://www.ncbi.nlm.nih.gov/pubmed/27631621
http://dx.doi.org/10.1371/journal.pgen.1006312