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XRN2 Autoregulation and Control of Polycistronic Gene Expresssion in Caenorhabditis elegans

XRN2 is a conserved 5’→3’ exoribonuclease that complexes with proteins that contain XRN2-binding domains (XTBDs). In Caenorhabditis elegans (C. elegans), the XTBD-protein PAXT-1 stabilizes XRN2 to retain its activity. XRN2 activity is also promoted by 3'(2'),5'-bisphosphate nucleotida...

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Detalles Bibliográficos
Autores principales: Miki, Takashi S., Carl, Sarah H., Stadler, Michael B., Großhans, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025045/
https://www.ncbi.nlm.nih.gov/pubmed/27631780
http://dx.doi.org/10.1371/journal.pgen.1006313