Small GSK-3 Inhibitor Shows Efficacy in a Motor Neuron Disease Murine Model Modulating Autophagy

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that has no effective treatment up to date. Drug discovery tasks have been hampered due to the lack of knowledge in its molecular etiology together with the limited animal models for research. Recently, a motor ne...

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Detalles Bibliográficos
Autores principales: de Munck, Estefanía, Palomo, Valle, Muñoz-Sáez, Emma, Perez, Daniel I., Gómez-Miguel, Begoña, Solas, M. Teresa, Gil, Carmen, Martínez, Ana, Arahuetes, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025054/
https://www.ncbi.nlm.nih.gov/pubmed/27631495
http://dx.doi.org/10.1371/journal.pone.0162723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025054/
https://www.ncbi.nlm.nih.gov/pubmed/27631495
http://dx.doi.org/10.1371/journal.pone.0162723

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