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Exceptional Heterogeneity in Viral Evolutionary Dynamics Characterises Chronic Hepatitis C Virus Infection

The treatment of HCV infection has seen significant progress, particularly since the approval of new direct-acting antiviral drugs. However these clinical achievements have been made despite an incomplete understanding of HCV replication and within-host evolution, especially compared with HIV-1. Her...

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Detalles Bibliográficos
Autores principales: Raghwani, Jayna, Rose, Rebecca, Sheridan, Isabelle, Lemey, Philippe, Suchard, Marc A., Santantonio, Teresa, Farci, Patrizia, Klenerman, Paul, Pybus, Oliver G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025083/
https://www.ncbi.nlm.nih.gov/pubmed/27631086
http://dx.doi.org/10.1371/journal.ppat.1005894