Cargando…
miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington’s Disease Monkey Neural Cells
Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the expansion of polyglutamine (polyQ) tract that leads to motor, cognitive and psychiatric impairment. Currently there is no cure for HD. A transgenic HD nonhuman primate (HD-NHP) model was developed with progressive dev...
Autores principales: | Kunkanjanawan, Tanut, Carter, Richard L., Prucha, Melinda S., Yang, Jinjing, Parnpai, Rangsun, Chan, Anthony W. S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025087/ https://www.ncbi.nlm.nih.gov/pubmed/27631085 http://dx.doi.org/10.1371/journal.pone.0162788 |
Ejemplares similares
-
Reversal of Cellular Phenotypes in Neural Cells Derived from Huntington’s Disease Monkey-Induced Pluripotent Stem Cells
por: Carter, Richard L., et al.
Publicado: (2014) -
Modeling Neurological Disorders by Human Induced Pluripotent Stem Cells
por: Kunkanjanawan, Tanut, et al.
Publicado: (2011) -
A Xeno-Free Strategy for Derivation of Human Umbilical Vein Endothelial Cells and Wharton's Jelly Derived Mesenchymal Stromal Cells: A Feasibility Study toward Personal Cell and Vascular Based Therapy
por: Kunkanjanawan, Hataiwan, et al.
Publicado: (2020) -
microRNA-128a dysregulation in transgenic Huntington’s disease monkeys
por: Kocerha, Jannet, et al.
Publicado: (2014) -
Monkey hybrid stem cells develop cellular features of Huntington's disease
por: Laowtammathron, Chuti, et al.
Publicado: (2010)