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Liposomal C6 Ceramide Activates Protein Phosphatase 1 to Inhibit Melanoma Cells

Melanoma is one common skin cancer. In the present study, the potential anti-melanoma activity by a liposomal C6 ceramide was tested in vitro. We showed that the liposomal C6 (ceramide) was cytotoxic and anti-proliferative against a panel of human melanoma cell lines (SK-Mel2, WM-266.4 and A-375 and...

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Detalles Bibliográficos
Autores principales: Jiang, Fangzhen, Jin, Kai, Huang, Shenyu, Bao, Qi, Shao, Zheren, Hu, Xueqing, Ye, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025141/
https://www.ncbi.nlm.nih.gov/pubmed/27631768
http://dx.doi.org/10.1371/journal.pone.0159849