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KLHDC10 Deficiency Protects Mice against TNFα-Induced Systemic Inflammation

Systemic inflammatory response syndrome (SIRS) is a form of fatal acute inflammation for which there is no effective treatment. Here, we revealed that the ablation of Kelch domain containing 10 (KLHDC10), which we had originally identified as an activator of Apoptosis Signal-regulating Kinase 1 (ASK...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Namiko, Sekine, Shiori, Naguro, Isao, Sekine, Yusuke, Ichijo, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025154/
https://www.ncbi.nlm.nih.gov/pubmed/27631783
http://dx.doi.org/10.1371/journal.pone.0163118