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Systems Biology-Based Investigation of Cellular Antiviral Drug Targets Identified by Gene-Trap Insertional Mutagenesis

Viruses require host cellular factors for successful replication. A comprehensive systems-level investigation of the virus-host interactome is critical for understanding the roles of host factors with the end goal of discovering new druggable antiviral targets. Gene-trap insertional mutagenesis is a...

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Detalles Bibliográficos
Autores principales: Cheng, Feixiong, Murray, James L., Zhao, Junfei, Sheng, Jinsong, Zhao, Zhongming, Rubin, Donald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025164/
https://www.ncbi.nlm.nih.gov/pubmed/27632082
http://dx.doi.org/10.1371/journal.pcbi.1005074