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Coenzyme Q10 plus Multivitamin Treatment Prevents Cisplatin Ototoxicity in Rats

Cisplatin (Cpt) is known to induce a high level of oxidative stress, resulting in an increase of reactive oxygen species damaging the inner ear and causing hearing loss at high frequencies. Studies on animal models show that antioxidants may lower Cpt-induced ototoxicity. The aim of this study is to...

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Detalles Bibliográficos
Autores principales: Astolfi, Laura, Simoni, Edi, Valente, Filippo, Ghiselli, Sara, Hatzopoulos, Stavros, Chicca, Milvia, Martini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025172/
https://www.ncbi.nlm.nih.gov/pubmed/27632426
http://dx.doi.org/10.1371/journal.pone.0162106