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Coenzyme Q10 plus Multivitamin Treatment Prevents Cisplatin Ototoxicity in Rats
Cisplatin (Cpt) is known to induce a high level of oxidative stress, resulting in an increase of reactive oxygen species damaging the inner ear and causing hearing loss at high frequencies. Studies on animal models show that antioxidants may lower Cpt-induced ototoxicity. The aim of this study is to...
Autores principales: | Astolfi, Laura, Simoni, Edi, Valente, Filippo, Ghiselli, Sara, Hatzopoulos, Stavros, Chicca, Milvia, Martini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025172/ https://www.ncbi.nlm.nih.gov/pubmed/27632426 http://dx.doi.org/10.1371/journal.pone.0162106 |
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