OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling

Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex. In this report, we tested the potential effect of OSU53, a novel AMPK...

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Detalles Bibliográficos
Autores principales: Xu, Dawei, Zhao, Wei, Zhu, Xinhui, Fan, Jianbo, Cui, Shengyu, Sun, Yuyu, Chen, Xiang, Liu, Wei, Cui, Zhi-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025189/
https://www.ncbi.nlm.nih.gov/pubmed/27632213
http://dx.doi.org/10.1371/journal.pone.0162694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025189/
https://www.ncbi.nlm.nih.gov/pubmed/27632213
http://dx.doi.org/10.1371/journal.pone.0162694

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