Cargando…
OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling
Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex. In this report, we tested the potential effect of OSU53, a novel AMPK...
Autores principales: | Xu, Dawei, Zhao, Wei, Zhu, Xinhui, Fan, Jianbo, Cui, Shengyu, Sun, Yuyu, Chen, Xiang, Liu, Wei, Cui, Zhi-ming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025189/ https://www.ncbi.nlm.nih.gov/pubmed/27632213 http://dx.doi.org/10.1371/journal.pone.0162694 |
Ejemplares similares
-
Activation of AMPK by OSU53 protects spinal cord neurons from oxidative stress
por: Xu, Jun, et al.
Publicado: (2017) -
microRNA-25 targets PKCζ and protects osteoblastic cells from dexamethasone via activating AMPK signaling
por: Fan, Jian-bo, et al.
Publicado: (2016) -
miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone
por: Fan, Jian-Bo, et al.
Publicado: (2016) -
Vitamin K2 Can Rescue the Dexamethasone-Induced Downregulation of Osteoblast Autophagy and Mitophagy Thereby Restoring Osteoblast Function In Vitro and In Vivo
por: Chen, Liang, et al.
Publicado: (2020) -
OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCδ/p53
por: Omar, Hany A., et al.
Publicado: (2016)