Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific qPCR

Establishing the KRAS mutational status of tumor samples is essential to manage patients with colorectal or lung cancer, since these mutations preclude treatment with monoclonal anti-epidermal growth factor receptor (EGFR) antibodies. We report an inexpensive, rapid multiplex allele-specific qPCR me...

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Detalles Bibliográficos
Autores principales: Orue, Andrea, Rieber, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025196/
https://www.ncbi.nlm.nih.gov/pubmed/27632281
http://dx.doi.org/10.1371/journal.pone.0163070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025196/
https://www.ncbi.nlm.nih.gov/pubmed/27632281
http://dx.doi.org/10.1371/journal.pone.0163070

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