Cargando…
Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific qPCR
Establishing the KRAS mutational status of tumor samples is essential to manage patients with colorectal or lung cancer, since these mutations preclude treatment with monoclonal anti-epidermal growth factor receptor (EGFR) antibodies. We report an inexpensive, rapid multiplex allele-specific qPCR me...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025196/ https://www.ncbi.nlm.nih.gov/pubmed/27632281 http://dx.doi.org/10.1371/journal.pone.0163070 |