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Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer
Chromatin-based DNA damage response (DDR) pathways are fundamental for preventing genome and epigenome instability, which are prevalent in cancer. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) catalyze the addition and removal of acetyl groups on lysine residues, a post-translat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025232/ https://www.ncbi.nlm.nih.gov/pubmed/27631103 http://dx.doi.org/10.1371/journal.pgen.1006272 |