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Formin-mediated actin polymerization at cell–cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair

Cadherin-mediated cell–cell adhesion is required for epithelial tissue integrity in homeostasis, during development, and in tissue repair. E-cadherin stability depends on F-actin, but the mechanisms regulating actin polymerization at cell–cell junctions remain poorly understood. Here we investigated...

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Detalles Bibliográficos
Autores principales: Rao, Megha Vaman, Zaidel-Bar, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025271/
https://www.ncbi.nlm.nih.gov/pubmed/27440924
http://dx.doi.org/10.1091/mbc.E16-06-0429