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Sox4 Mediated Dicer Expression is Critical for Suppression of Melanoma Cell Invasion

We previously reported reduced expression of Sox4 in metastatic melanoma and its role in suppression of cell migration and invasion through inhibition of NF-κB p50. Sox4 can also bind to the promoter sequence of Dicer, a miRNA biogenesis factor. Interestingly, altered expression of Dicer was also ob...

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Detalles Bibliográficos
Autores principales: Jafarnejad, Seyed Mehdi, Ardekani, Gholamreza Safaee, Ghaffari, Mazyar, Martinka, Magdalena, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025280/
https://www.ncbi.nlm.nih.gov/pubmed/22689055
http://dx.doi.org/10.1038/onc.2012.239