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Sox4 Mediated Dicer Expression is Critical for Suppression of Melanoma Cell Invasion
We previously reported reduced expression of Sox4 in metastatic melanoma and its role in suppression of cell migration and invasion through inhibition of NF-κB p50. Sox4 can also bind to the promoter sequence of Dicer, a miRNA biogenesis factor. Interestingly, altered expression of Dicer was also ob...
Autores principales: | Jafarnejad, Seyed Mehdi, Ardekani, Gholamreza Safaee, Ghaffari, Mazyar, Martinka, Magdalena, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025280/ https://www.ncbi.nlm.nih.gov/pubmed/22689055 http://dx.doi.org/10.1038/onc.2012.239 |
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