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Nodal promotes invasive phenotypes via a Mitogen Activated Protein Kinase-dependent pathway
The progression of cancer from localized to invasive disease is requisite for metastasis, and is often characterized by epithelial-to-mesenchymal transition (EMT) and alterations in cellular adhesion and migration. Studies have shown that this transition is associated with an up-regulation of embryo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025281/ https://www.ncbi.nlm.nih.gov/pubmed/23334323 http://dx.doi.org/10.1038/onc.2012.608 |