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Design of a stable cell line producing a recombinant monoclonal anti-TNFα antibody based on a CHO cell line

Recombinant monoclonal antibodies (mAbs) against tumor necrosis factor alpha are widely used in the biopharmaceutical therapy of autoimmune diseases. Currently, a large number of drugs based on these antibodies are available. Accordingly, the development of these products for the Russian market is a...

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Detalles Bibliográficos
Autores principales: Voronina, E. V., Seregin, Y. A., Litvinova, N. A., Shvets, V. I., Shukurov, R. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025404/
https://www.ncbi.nlm.nih.gov/pubmed/27652157
http://dx.doi.org/10.1186/s40064-016-3213-2