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Imatinib could be a new strategy for pulmonary hypertension caused by pulmonary tumor thrombotic microangiopathy in metastatic breast cancer

INTRODUCTION: Pulmonary tumor thrombotic microangiopathy (PTTM) is rare, cancer-related pulmonary complication leading to hypoxia, pulmonary hypertension, and heart failure. The standard treatment for PTTM is not established. However, imatinib, a tyrosine kinase inhibitor of the PDGF receptor, may c...

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Detalles Bibliográficos
Autores principales: Fukada, Ippei, Araki, Kazuhiro, Kobayashi, Kokoro, Shibayama, Tomoko, Hatano, Masaru, Takahashi, Shunji, Iwase, Takuji, Ohno, Shinji, Ito, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025414/
https://www.ncbi.nlm.nih.gov/pubmed/27652155
http://dx.doi.org/10.1186/s40064-016-3280-4