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Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome

BACKGROUND: Centrifugation is an indispensable procedure for plasma sample preparation, but applied conditions can vary between labs. AIM: Determine whether routinely used plasma centrifugation protocols (1500×g 10 min; 3000×g 5 min) influence non-targeted metabolomic analyses. METHODS: Nuclear magn...

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Detalles Bibliográficos
Autores principales: Lesche, Dorothea, Geyer, Roland, Lienhard, Daniel, Nakas, Christos T., Diserens, Gaëlle, Vermathen, Peter, Leichtle, Alexander B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025507/
https://www.ncbi.nlm.nih.gov/pubmed/27729833
http://dx.doi.org/10.1007/s11306-016-1109-3