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Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

BACKGROUND: The advent of whole-genome sequencing has generated increased interest in modelling the structure of strain mixture within clinical infections of Plasmodium falciparum The life cycle of the parasite implies that the mixture of multiple strains within an infected individual is related to...

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Detalles Bibliográficos
Autores principales: O’Brien, John D., Amenga-Etego, Lucas, Li, Ruiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025560/
https://www.ncbi.nlm.nih.gov/pubmed/27634595
http://dx.doi.org/10.1186/s12936-016-1531-z