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Direct reprogramming of urine-derived cells with inducible MyoD for modeling human muscle disease
BACKGROUND: Cellular models of muscle disease are taking on increasing importance with the large number of genes and mutations implicated in causing myopathies and the concomitant need to test personalized therapies. Developing cell models relies on having an easily obtained source of cells, and if...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025576/ https://www.ncbi.nlm.nih.gov/pubmed/27651888 http://dx.doi.org/10.1186/s13395-016-0103-9 |