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Direct reprogramming of urine-derived cells with inducible MyoD for modeling human muscle disease

BACKGROUND: Cellular models of muscle disease are taking on increasing importance with the large number of genes and mutations implicated in causing myopathies and the concomitant need to test personalized therapies. Developing cell models relies on having an easily obtained source of cells, and if...

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Detalles Bibliográficos
Autores principales: Kim, Ellis Y., Page, Patrick, Dellefave-Castillo, Lisa M., McNally, Elizabeth M., Wyatt, Eugene J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025576/
https://www.ncbi.nlm.nih.gov/pubmed/27651888
http://dx.doi.org/10.1186/s13395-016-0103-9