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Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlations

BACKGROUND: In chronic lymphocytic leukemia (CLL), next-generation sequencing (NGS) analysis represents a sensitive, reproducible, and resource-efficient technique for routine screening of gene mutations. METHODS: We performed an extensive biologic characterization of newly diagnosed CLL, including...

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Detalles Bibliográficos
Autores principales: Rigolin, Gian Matteo, Saccenti, Elena, Bassi, Cristian, Lupini, Laura, Quaglia, Francesca Maria, Cavallari, Maurizio, Martinelli, Sara, Formigaro, Luca, Lista, Enrico, Bardi, Maria Antonella, Volta, Eleonora, Tammiso, Elisa, Melandri, Aurora, Urso, Antonio, Cavazzini, Francesco, Negrini, Massimo, Cuneo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025606/
https://www.ncbi.nlm.nih.gov/pubmed/27633522
http://dx.doi.org/10.1186/s13045-016-0320-z