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Genome-wide positioning of bivalent mononucleosomes

BACKGROUND: Bivalent chromatin refers to overlapping regions containing activating histone H3 Lys4 trimethylation (H3K4me3) and inactivating H3K27me3 marks. Existence of such bivalent marks on the same nucleosome has only recently been suggested. Previous genome-wide efforts to characterize bivalent...

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Detalles Bibliográficos
Autores principales: Sen, Subhojit, Block, Kirsten F., Pasini, Alice, Baylin, Stephen B., Easwaran, Hariharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025636/
https://www.ncbi.nlm.nih.gov/pubmed/27634286
http://dx.doi.org/10.1186/s12920-016-0221-6