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Improved Transgenic Mouse Model for Studying HLA Class I Antigen Presentation

HLA class I (HLA-I) transgenic mice have proven to be useful models for studying human MHC-related immune responses over the last two decades. However, differences in the processing and presentation machinery between humans and mice may have profound effects on HLA-I restricted antigen presentation....

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Detalles Bibliográficos
Autores principales: Huang, Man, Zhang, Wei, Guo, Jie, Wei, Xundong, Phiwpan, Krung, Zhang, Jianhua, Zhou, Xuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025652/
https://www.ncbi.nlm.nih.gov/pubmed/27634283
http://dx.doi.org/10.1038/srep33612