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TGF-β1 autocrine signalling and enamel matrix components

Transforming growth factor-β1 (TGF-β1) is present in porcine enamel extracts and is critical for proper mineralization of tooth enamel. Here, we show that the mRNA of latent TGF-β1 is expressed throughout amelogenesis. Latent TGF-β1 is activated by matrix metalloproteinase 20 (MMP20), coinciding wit...

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Detalles Bibliográficos
Autores principales: Kobayashi-Kinoshita, Saeko, Yamakoshi, Yasuo, Onuma, Kazuo, Yamamoto, Ryuji, Asada, Yoshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025654/
https://www.ncbi.nlm.nih.gov/pubmed/27633089
http://dx.doi.org/10.1038/srep33644