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Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7)

Transient receptor potential melastatin 7 (TRPM7) is a ubiquitously expressed Mg(2+)-permeable ion channel fused to a C-terminal α-kinase domain. Recently, aldosterone was shown to increase intracellular Mg(2+) levels and alter inflammatory signaling in TRPM7-expressing HEK293 cells. This study was...

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Detalles Bibliográficos
Autores principales: Valinsky, William C., Jolly, Anna, Miquel, Perrine, Touyz, Rhian M., Shrier, Alvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025699/
https://www.ncbi.nlm.nih.gov/pubmed/27466368
http://dx.doi.org/10.1074/jbc.M116.735175