The N-terminal domain plays a crucial role in the structure of a full-length human mitochondrial Lon protease

Lon is an essential, multitasking AAA(+) protease regulating many cellular processes in species across all kingdoms of life. Altered expression levels of the human mitochondrial Lon protease (hLon) are linked to serious diseases including myopathies, paraplegia, and cancer. Here, we present the firs...

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Detalles Bibliográficos
Autores principales: Kereïche, Sami, Kováčik, Lubomír, Bednár, Jan, Pevala, Vladimír, Kunová, Nina, Ondrovičová, Gabriela, Bauer, Jacob, Ambro, Ľuboš, Bellová, Jana, Kutejová, Eva, Raška, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025710/
https://www.ncbi.nlm.nih.gov/pubmed/27632940
http://dx.doi.org/10.1038/srep33631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025710/
https://www.ncbi.nlm.nih.gov/pubmed/27632940
http://dx.doi.org/10.1038/srep33631

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